A Cumulative Approach on Rare Case of Infantile Tremor Syndrome

Infantile Tremor Syndrome (ITS) is categorically determined as a self-limiting clinical presentation which is characterized by anaemia, tremors, pigmentary skin disease, muscular hypotonia, and mental development regression. The presenting tremors are coarse in nature which are either decreased or vanished during sleep and takes 4-6 weeks duration for complete resolution following its natural course. The aetiology for ITS has been hypothesized for various factors like metabolic, infectious, nutritional but remained inconclusive for effective statement. But the precipitation is on the developing deficiency of Vitamin B12 but it remained controversial in terms of different factors. As the aetiology remained undefined, the line of treatment for children with ITS has been considered as per the treatment for undernourished child which included nutritional management with external supplementation of trace elements like iron, magnesium, calcium, vitamin B12 along with other such multivitamins. The administration of tremors is most commonly managed with the administration of propranolol or phenytoin, phenobarbitone, and carbamazepine.
An 8 months old male child was brought by parents with complaints of fever since 8 days, decreased appetite and vomiting since 3 days. The course of hospital followed by physiotherapy which helped in regaining the normal functional activity of the baby.