Cholecystokinin in the Pathogenesis of Bulimia Nervosa

López, Helena Trebbau and Molina-Ruiz, Rosa María and Molón, Laura Reyes and Díaz-Marsá, Marina (2011) Cholecystokinin in the Pathogenesis of Bulimia Nervosa. International Journal of Clinical Medicine, 02 (04). pp. 509-515. ISSN 2158-284X

[thumbnail of IJCM20110400025_65107728.pdf] Text
IJCM20110400025_65107728.pdf - Published Version

Download (152kB)

Abstract

Objective: This review aims to describe the role of the hormone cholecystokinin (CCK) in the pathogenesis of bulimia nervosa (BN), the perpetuation of this illness and the possibility of its use as a target for future therapeutic advances. Methods: Search for cholecystokinin AND bulimia nervosa in Pubmed Central, with no limits, identified 38 articles published up to the present date. Results: It is well established that CCK is altered in the pathogenesis of BN, and that its main role is in the perpetuation of the disorder rather than the cause of it. Discussion: Additional studies will be needed to further understand the mechanisms by which CCK regulates orexigenic pathways. If an orally active, longer acting analogue of CCK could be developed, it would be of significant interest as an appetite suppressant and a key adjuvant in the treatment of patients suffering from BN, particularly in refractory cases.

Item Type: Article
Subjects: Pustaka Library > Medical Science
Depositing User: Unnamed user with email support@pustakalibrary.com
Date Deposited: 16 Jan 2023 11:10
Last Modified: 03 Jan 2024 07:04
URI: http://archive.bionaturalists.in/id/eprint/38

Actions (login required)

View Item
View Item