Potential Biomedical Effects of Durio zibethinus Extract Mediated Gold Nanoparticles as Antimicrobial, Antioxidant and Anticoagulant Activity

Nanotechnology is an innovative branch of science that deals with the formation, processing, and applications of nanomaterials. An eco-friendly and efficient method has been used for the green synthesis of stable gold nanoparticles (Au NPs) using Durio zibethinus extract as a reducing and capping agent. Durio zibethinus seeds were extracted from fresh, methodically washed Durio fruits obtained from Bangalore Fruit Market, India. In the present work, the green synthesis method was employed to obtain Au NPs with the assistance of Durio zibethinus seeds extract as a reducing agent and capping agent. The biologically produced nanoparticles were characterized by UV-Vis, XRD, SEM, EDAX and TEM analysis. The elemental composition of Au NPs was reported by EDAX spectral analysis. The bio-reduced Au NPs exhibited almost spherical. Increasing applications of NPs, especially metallic nanoparticles plays an important role. Gold is one of the most useful metallic nanoparticles. Au NPs have unique physiochemical characteristics and wide usage in different field applications. Besides, the antibacterial, antioxidant and anticoagulant properties of Au NPs were studied. It is proved that Au NPs synthesized using natural reducing agents (plant leaves, route, seeds, pulp, stem, etc.) are eco-friendly, inexpensive, and have good anti-microbial activities against micro-organisms. This study established a synthesis of Au NPs using Durio zibethinus extract as a viable green route approach, with remarkable antimicrobial, antioxidant and anticoagulant activities. Overall, the green synthesized Au NPs will be useful in the biomedical and materials industries. As far as we know, this study is the first report of the use of Durio zibethinus extract to synthesize Au NPs.