A Comparison and Evaluation of Loop Diuretic Frusemide Generic vs Brand Tablets

Branded medications are the original products developed by pharmaceutical companies and generic drugs are copies of branded drugs whose patent has expired. The research work focused on comparisons and evaluations of generic VS brand of frusemide tablets. The study includes some of the specifications that should tested in the finished products in tablets such as appearance, thickness, diameter, weight variation, hardness, friability, disintegration time, dissolution, hardness and thickness as per pharmacopoeial & non pharmacopoeial tests were performed. The generic and brand frusemide tablets quality control results showed within the range as per IP. The in vitrodrug release of generic frusemide tablets was found to be 96.7 %in 45 min and branded tablets which showed drug release 98.3% in 45 min. Hence, it can be concluded that evaluation of loop diuretic frusemide tablets generic and brand frusemide tablets showed same deviations in the quality control results as per IP.