Clinical Features, Diagnosis, and Management of Vogt-Koyanagi-Harada Disease in a Tertiary Care Hospital in Late Stage

This chapter discuss about clinical features, diagnosis, and management of Vogt-Koyanagi-Harada disease. Vogt-Koyanagi-Harada disease (VKHD), initially described as an uveomeningoencephalitic syndrome, is a systemic granulomatous autoimmune disease that targets melanocyte-rich tissues, such as the eye, inner ear, meninges, skin and hair. VKHD is difficult to diagnose because its clinical presentation is variable and multisystemic which often leads to late diagnosis and treatment allowing the appearance and progression of the disease sequelae. We report a 35-year-old female presented to our hospital with chief complaints of pain, redness, and progressive diminution of vision in both eyes for 2 years. Early referral to tertiary centers should be the golden rule, as delay in initiation of treatment can lead to secondary complications such as serous retinal detachment, cataract, glaucoma, choroidal.