Study on Genome Sequencing Practices as Driving Force of Clinical Research Modernization in the Future

Genome sequencing is one of the latest technologies to be introduced into medical practices for disease diagnostic and clinical trials for drugs discovery. It is often used in the practices of genomic medicine, to process and analyze genes and markers information to diagnose and treat disease. Specifically, genomic medicine uses DNA and RNA platform sequencing technologies to analyze human genome to detect, mutation, molecular abnormalities with clear clinical significances that may be associated to rare genetic diseases. The Human Genome Sequencing Project, which found around 35,000 genes in sequences of more than 3 billion human DNA and RNA chemical bases, was completed in 2003 with the use of these genomic sequencing platforms (first- and second-generation sequencing technologies). This cleared the door for genomic medicine, allowing researchers to conduct translational genomic clinical trials, which have advanced the clinical trial process in a variety of ways.